Index Catalog // Hyrax

Duke OB/GYN Magazine (Winter 2023)

Descrição:	Duke Department of Obstetrics & Gynecology's DUKE OB/GYN Magazine, Winter 2023
Data Criada:	Winter 2023

Duke Nursing Magazine (Spring/Summer 2023, Volume 19, No. 1)

Descrição:	Web resource for Duke Nursing Magazine, Spring/Summer 2023, Volume 19, No. 1
Data Criada:	Spring/Summer 2023

Social Determinants of Health Cluster Hire Initiative

Descrição:	Web resource for Duke University School of Nursing's publication, "Social Determinants of Health Cluster Hire Initiative".
Data Criada:	2023

Preventing Pediatric Accidental Decannulation Events: A Quality Improvement Initiative at a Tertiary Care Center

Descrição:	Background: Tracheostomy is a high-risk procedure in children under three years old, with a rate of major post-operative complications as high as 24%. The rate of accidental decannulation (AD), a common complication of tracheostomy associated...
Data Criada:	August 3-4, 2023

Using Clinical Phenotypes to Identify Populations with NAFLD or NASH: A Health System Approach

Descrição:	Background Despite causing significant morbidity and mortality, non-alcoholic fatty liver disease (NAFLD) is significantly underdiagnosed. Clinical indices developed to easily identify patients with hepatic steatosis and risk for more advanced...
Data Criada:	August 3-4, 2023

Food insecurity is associated with decreased access to care among people living with HIV and non-communicable diseases in Western Kenya

Descrição:	Background: It remains unclear whether food insecurity as a marker of poverty is a barrier to accessing health care in low-resource settings, or rather increases care utilization due to more frequent need for care. This study used baseline data...
Data Criada:	August 3-4, 2023

Long-Term Outcomes with Reduced-dose Whole Brain Radiotherapy and a Stereotactic Radiosurgery Boost for Primary CNS Lymphoma

Descrição:	Funding: National Institutes of Health/National Cancer Institute StARR Program R38 (5R38-CA245204 to E.J.V.); National Institutes of Health/National Cancer Institute (K08-CA2560450 to Z.J.R.). Background: Primary central nervous system lymphoma...
Data Criada:	August 3-4, 2023

Longitudinal Retinal Findings in Individuals with Mild Cognitive Impairment over a Two Year Period

Descrição:	Purpose The diagnosis of neurodegenerative diseases is largely based on clinical suspicion with limited confirmation antemortem. However, neuropathological changes occur years prior to disease presentation. Changes in the retina, an...
Data Criada:	August 3-4, 2023

Repeatability of Choroidal Imaging Metrics in Handheld versus Tabletop OCT images in Adults

Descrição:	Purpose: Few studies have looked at repeatability of the choroidal vascularity index (CVI) in different OCT imaging modalities. We performed a retrospective image analysis to compare a handheld swept-source research OCT system (UC3) to a gold...
Data Criada:	August 3-4, 2023

How Then Shall We Care? Sustaining surgery in rural Sudan

Descrição:	Introduction: The Lancet Commission on Global Surgery (2015) outlined several factors needed to sustain a workforce in austere settings. Yet, there is a paucity of literature exploring the personal narratives of these workforce members. There is...
Data Criada:	August 3-4, 2023

Obesity predisposes anthracycline-treated survivors of childhood and adolescent cancers to subclinical cardiac dysfunction detectable by strain echocardiography

Descrição:	Background Anthracyclines are effective chemotherapeutics used in >60% of pediatric cancer cases but have a well-documented risk of cardiotoxicity. Existing cardiotoxicity risk calculators do not include cardiovascular risk factors present...
Data Criada:	August 3-4, 2023

Impact of prosthetic joint infection on patient reported depression measures in hip and knee arthroplasty

Descrição:	Introduction: Prosthetic joint infection (PJI) following joint arthroplasty is a devastating complication. Prior studies have documented an association between PJI and increased prevalence of preoperative depression and elevated risk of new...
Data Criada:	August 3-4, 2023

Non-neutralizing SARS-CoV-2 N-terminal domain antibodies protect against infection using Fc effector functions

Descrição:	Antibodies perform both neutralizing and non-neutralizing functions that protect against certain pathogens. A human antibody directed at the SARS-CoV-2 spike protein N-terminal domain (NTD), DH1052, was recently shown to be non-neutralizing yet...
Data Criada:	August 3-4, 2023

Racial discrimination and risk factors for preeclampsia

Descrição:	Introduction: While obesity and chronic hypertension are often viewed as confounding the observed relationship between race and maternal morbidity, evidence suggests racism drives development of maternal morbidity risk factors, including obesity...
Data Criada:	August 3-4, 2023

Disease Course and Response to Immunotherapy in Children with Childhood Disintegrative Disorder: a retrospective case series

Descrição:	Childhood Disintegrative Disorder (CDD) is a poorly understood neurobehavioral disorder of early childhood characterized by acute to subacute profound regression in previously developed language, social behavior, and adaptive functions. The...
Data Criada:	August 3-4, 2023

Assessing the Impact of Healthcare Equity and Social Determinants of Health to Conservative Treatment in Adolescent Idiopathic Scoliosis

Descrição:	Healthcare inequities in the US impact access to medical treatment for pediatric patients, particularly in conditions like adolescent idiopathic scoliosis (AIS) where nonoperative management is effective. AIS affects 3% of the pediatric...
Data Criada:	August 3-4, 2023

Comparison of Postoperative Pain and Analgesic Consumption for Primary versus Repeat Cesarean Deliveries: A Retrospective Cohort Study

Descrição:	Introduction: It is currently unclear if postoperative pain experience differs in patients undergoing primary versus repeat cesarean deliveries, with prior studies reporting conflicting results. For instance, some studies have suggested that...
Data Criada:	August 3-4, 2023

Print-to-Patient: 3D Printing for Optimizing Breast Reconstruction

Descrição:	PURPOSE: Three-dimensional (3D) printing enables surgeons to take a more individualized approach to patient management. Commercially available scanning systems can be prohibitively expensive. Fortunately, high-quality 3D imaging is becoming...
Data Criada:	August 3-4, 2023

Full Weight-Bearing after dual-fixation of clavicle fractures appears safe and effective: a multicenter comparative study

Descrição:	INTRODUCTION Recently, dual-plating of displaced clavicle fractures has become a popular construct to reduce implant prominence while optimizing balanced fixation. Traditionally patients have a limited weight bearing period after clavicle...
Data Criada:	August 3-4, 2023

A Novel Approach to Percutaneous Lumbar Surgeries via Kambin’s Triangle - A Radiographic and Surgical Planning Analysis with Nerve Segmentation Technology

Descrição:	Background: While Kambin’s triangle has become an ever more important anatomic window given its proximity to the nerve root, there have been limited studies examining the effect of disease on the corridor. Recent studies have begun implementing 3D...
Data Criada:	August 3-4, 2023

Dual sample Optical Coherence Tomography using custom software and hardware

Descrição:	Background: Optical Coherence Tomography (OCT) is a routine and vital part of the Ophthalmology exam. OCT generates contrast by using light interference generated by tissue reflectivity; simply, it can be thought of akin to ultrasound, but using...
Data Criada:	August 3-4, 2023

Characterization and Localization of Focal Atrial Tachycardia in Adults with Congenital Heart Disease

Descrição:	Introduction: Patients with adult congenital heart disease (ACHD) often develop atrial arrhythmias, including focal atrial tachycardia (FAT). In non-ACHD patients, algorithms using surface ECG P-wave morphology are helpful to predict FAT location...
Data Criada:	August 3-4, 2023

Development and Characterization of a Gastric Organoid Biobank for Gastric Cancer Prevention and Interception

Descrição:	Background: In the United States, significant disparities exist in gastric cancer incidence and mortality between Black Americans and non-Hispanic White Americans. Helicobacter pylori (Hp) infection is the greatest risk factor for developing...
Data Criada:	August 3-4, 2023

Inferior Outcomes for Patients Transferred Between Surgical Stages for Knee Periprosthetic Joint Infection

Descrição:	Background: Periprosthetic joint infection (PJI) in total knee arthroplasty (TKA) may result in 2-stage revision surgery. There is limited data describing outcomes when the first stage is completed at an outside hospital and the patient is...
Data Criada:	August 3-4, 2023

Antibiotic Use and Predictors of H. pylori Eradication as Part of the Gastric Immune Response and Cancer Interception Translational (GRACE) Project

Descrição:	Acknowledgement: This project received NIH funding for Cancer Disparities research P20-CA251657 Background: Helicobacter pylori (Hp) is the strongest risk factor for non-cardia gastric adenocarcinoma, the cancer with the greatest racial...
Data Criada:	August 3-4, 2023

A blinded study using laser induced endogenous fluorescence spectroscopy to differentiate ex vivo spine tumor, healthy muscle, and healthy bone

Descrição:	Background Neurosurgical resection of tumors requires discernment of tumor from healthy tissue. Endogenous fluorophores exist in different concentrations in tissue enabling the classification of tissue type via excitation with a low power laser....
Data Criada:	August 3-4, 2023

Improving Health Literacy of Elective Procedures in Pediatric Otolaryngology

Descrição:	Introduction: In the pediatric otolaryngology setting, health literacy of patients and guardians has been shown to be overall highly proficient but has not been thoroughly examined at the level of understanding of the actual procedures being...
Data Criada:	August 3-4, 2023

Angioarchitectural Alterations in the Retina and Choroid in Frontotemporal Dementia

Descrição:	Background: Frontotemporal dementia (FTD) is a progressive neurodegenerative disorder that affects the frontal and temporal lobes of the brain, leading to cognitive decline and personality changes. Early detection of FTD is critical for initiating...
Data Criada:	August 3-4, 2023

Social Media Usage by Plastic Surgery Subspecialty Fellowship Programs

Descrição:	Background: Social media utilization in plastic surgery training has been growing exponentially since 2010. The importance of social media for integrated plastic surgery residency programs has already been well-demonstrated in the literature, with...
Data Criada:	August 3-4, 2023

Daily administration of Resolvin E1 has transient effect on diabetic bladder dysfunction in Akita male mice

Descrição:	Background: One of the most common but least studied complications of diabetes is diabetic bladder dysfunction. Current therapies for diabetic bladder dysfunction include glucose control and symptom-based interventions. However, there is mixed...
Data Criada:	August 3-4, 2023

The Duke Lung Nodule Database: A Reference Database for Lung Cancer Risk Classification of Low-Dose Screening Thoracic CT Scans

Descrição:	Background: Lung cancer risk classification is an increasingly important area of research as low-dose thoracic CT screening programs become standard of care for patients at high risk for lung cancer. There is limited availability of large,...
Data Criada:	August 3-4, 2023

Co-expression of Leukocyte Cytosolic Protein 1 and Matrix Metalloproteinases are Integral for Metastatic Progression of Chondrosarcoma

Descrição:	Background: Chondrosarcoma (CSA) lacks effective systemic therapies for metastatic disease. Thus, novel targets are necessary. Our previous work identified overexpression of Leukocyte Cytosolic Protein 1 (LCP1) in metastasizing CSAs and expression...
Data Criada:	August 3-4, 2023

Outcomes With a Mobile Digital Health Platform for Patients Undergoing Spine Surgery: Retrospective Analysis

Descrição:	Introduction Digital health solutions have been shown to improve outcomes for chronic medical conditions, but relatively few solutions have been validated for patients undergoing surgery. The digital health platform ManageMySurgery (MMS) has...
Data Criada:	August 3-4, 2023

Systematic Review of Skin Cancer within Tattoos

Descrição:	Background: Tattooing is a widespread practice and has increased in popularity over time. A recent poll suggests that 30% of Americans have at least one tattoo, which has increased from 21% reported in 2012. Many lesions have been described in...
Data Criada:	August 3-4, 2023

Biologic Effects of Allostasis

Descrição:	Introduction Allostasis is the process by which the body responds to environmental stressors to maintain physiological functioning. When allostasis is maintained at a moderate level, it serves as a beneficial mechanism to cope with the daily...
Data Criada:	August 3-4, 2023

Impact of Reducing Deductible Levels on Health Care Utilization, Quality, and Costs Among Diabetes Patients

Descrição:	Background Out-of-pocket (OOP) costs have been increasing for commercially insured people. These high OOP costs are associated with suboptimal outcomes, particularly impacting low-income patients with diabetes. An increasing number of employers...
Data Criada:	August 3-4, 2023

TET2 Mutations in Chronic Myeloid Neoplasia are Associated with Large Vessel Inflammation

Descrição:	Introduction: Chronic myeloid neoplasia (CMN) describes the clonal outgrowth of blood cells from abnormal hematopoietic stem cells and includes both malignancies and pre-malignant states. Previous work has associated CMN with surgically-relevant...
Data Criada:	August 3-4, 2023

The Impact of Significant Ischemic Heart Disease Events on Spiritual & Religious Wellbeing: A Qualitative Interview Study and Grounded Theory Analysis

Descrição:	Background Severe and life-threatening illness can be a significant source of suffering for patients. This suffering can include mental anxiety, financial strain, and spiritual questioning. Between one third and one half of Americans will die...
Data Criada:	August 3-4, 2023

Use of Pediatric Trauma Simulations to Facilitate Exposure to Pediatric Trauma Resuscitations During Training

Descrição:	Background: Pediatric traumas are often high-acuity, but low-frequency compared to adult trauma activations. This is reflected by the relatively limited experience with these events during training. While some principles of trauma resuscitation...
Data Criada:	August 3-4, 2023

Effects of submersion on maximal oxygen uptake (V̇O2): comparing aerobic exertion on land and underwater

Descrição:	Introduction: Diving is a physically demanding activity requiring much energy and stamina. A fit diver is less likely to become fatigued during a dive, which reduces the risk of accidents and injuries. Few studies have been performed to compare...
Data Criada:	August 3-4, 2023

Weight Stigma in Providers: A Qualitative Study on Provider Attitudes Towards Eating Disorders and Obesity

Descrição:	Background: Eating disorders (EDs) are widely prevalent in the US, have some of the highest mortality rates reported among psychiatric illnesses, and can be exacerbated by stigmatization against EDs. Similarly, obesity is generally recognized as a...
Data Criada:	August 3-4, 2023

Extracellular vesicle-derived HIV RNA in CSF and serum reservoirs and its role in mediating neurocognitive dysfunction

Descrição:	Background Approximately 37 million people are infected with HIV-1, which causes acquired immunodeficiency syndrome (AIDS) and is among leading global causes of both mortality and burden. While combined antiretroviral therapy (cART) has...
Data Criada:	August 3-4, 2023

Aging and the female urinary microbiome: associations between Lactobacilli, menopause, and vaginal estrogen

Descrição:	INTRODUCTION: The urogenital microbiome, including microbes in the urinary bladder and vagina, demonstrates variations that are linked to aging. While prior studies have shown how the composition of the vaginal microbiome changes after menopause,...
Data Criada:	August 3-4, 2023

Key Drivers of 90-day Costs in Primary Total Elbow Arthroplasty

Descrição:	Background: Progress towards value-based care in orthopaedics requires knowledge on surgical care costs as well as drivers of costs. Therefore, the purpose of this study was to assess 90-day health system costs in primary total elbow arthroplasty...
Data Criada:	August 3-4, 2023

Exploration of a Potential DOOR Endpoint for Complicated Intra-Abdominal Infections Using Nine Registrational Trials for Antibacterial Drugs

Descrição:	Background Desirability of outcome ranking (DOOR) is a novel approach to clinical trial design that incorporates safety and efficacy assessments into an ordinal ranking system to evaluate overall outcomes of clinical trial participants. Here, we...
Data Criada:	August 3-4, 2023

Impact of Medically-Supervised Weight Loss on Patient-Reported Outcomes After Total Knee Arthroplasty

Descrição:	Background: Weight loss is commonly recommended before total knee arthroplasty (TKA) despite inconsistent evidence for better outcomes. The purpose of this study was to examine the impact of weight loss before TKA on adverse events and...
Data Criada:	August 3-4, 2023

Limited English Proficiency and Self-Rated Health in Latinx Young Adults

Descrição:	People with Limited English Proficiency (LEP) are at risk for suboptimal health outcomes, health care disparities in health care access, and face intersecting challenges in the healthcare system. More than 25 million individuals report LEP and...
Data Criada:	August 3-4, 2023

Efficacy and Impact of 1-week postpartum mood check

Descrição:	Objective: Postpartum mood disorders, including depression, anxiety, and postpartum psychosis, affect up to 20% of new mothers. Despite the prevalence and potential severity of postpartum mood disorders, they often go undetected and untreated....
Data Criada:	August 3-4, 2023

A Mixed-Methods Feasibility Study of Noninvasive Intracranial Pressure Monitoring for Adults After Traumatic Brain Injury in Uganda

Descrição:	Funding for this work was provided by Duke Global Health Institute and Duke Global Neurosurgery and Neurology. Background: Traumatic brain injury (TBI) accounts for the majority of Uganda’s neurosurgical disease burden; however, invasive...
Data Criada:	August 3-4, 2023

Sleep disturbances and associated health and psychosocial risk factors in adolescents who identify as transgender/non-binary

Descrição:	Scholarship/funding: This research did not receive any specific grant or scholarship from funding agencies in the public, commercial or not-for-profit sectors. Background: Sleep disturbance, such as insomnia and short sleep duration, is...
Data Criada:	August 3-4, 2023

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