Index Catalog // MEDSpace

The Impact of Patient-Centered Medical Homes on Healthcare Outcomes

Description/Abstract:	The American Academy of Pediatrics coined the term “medical home” in 1967 for establishing a single source of care and medical record for children with special health care needs. This phenomenon has expanded across multiple disciplines and more...
Date:	March 2022

James M. Douglas Oral History Interview, 2022

Description/Abstract:	This oral history interview was conducted with Dr. James M. Douglas on February 1, 2022 by Konstantinos Economopoulos as part of the Dr. David Sabiston Oral History Project. During the interview, Douglas discusses his early life; education; why...
Date:	2022-02-01

Don E. Detmer Oral History Interview, 2022

Description/Abstract:	This oral history interview was conducted with Dr. Don E. Detmer on February 2, 2022 by Dr. Konstantinos Economopoulos as part of the Dr. David Sabiston Oral History Project. During the interview, Detmer discusses his early life, education, his...
Date:	2022-02-02

Canine Patient-Derived Organoids as a Model of Tumor Heterogeneity and Drug Sensitivity in Osteosarcoma

Description/Abstract:	Background: The rare and heterogenous nature of osteosarcoma (OSA) has made it difficult to study and limited clinical breakthroughs. Traditional cell culture fails to recreate tumor heterogeneity and murine xenografts take extended time to study....
Date:	August 5, 2022

Prevalence and Economic Burden of Depression and Anxiety Among Singaporean Adults: Results from a Web Panel

Description/Abstract:	Background: Most estimates for the prevalence of depression and anxiety predate COVID-19, which has had a detrimental effect on mental health worldwide. While some literature has been published recently on the rise in prevalence of mental health...
Date:	August 5, 2022

Interneuron transplantation in a mouse organotypic epilepsy model

Description/Abstract:	Background Cortical GABAergic interneurons are generated from one of the proliferative zones in the ventral telecephalon called the medial ganglionic eminence (MGE) during embryonic development. These interneurons are important for regulating...
Date:	August 5, 2022

Obstructive Sleep Apnea as a Risk Factor for Postoperative Cognitive Dysfunction and Postoperative Delirium

Description/Abstract:	Background: Up to 40% of older surgical patients develop postoperative delirium (POD) and/or postoperative cognitive dysfunction (POCD)–objective cognitive deficits occurring 1-12 months after surgery. Although POCD and POD are both associated...
Date:	August 5, 2022

Automatic Breast, Fibroglandular Tissue, and Blood Vessel Segmentation in Breast MRI using Convolutional Neural Networks

Description/Abstract:	Background Breast density, or the amount of fibroglandular tissue (FGT) present relative overall breast volume, has been shown in multiple studies to increase the risk of developing breast cancer. Breast density is typically assessed...
Date:	August 5, 2022

A Machine Learning Model to Improve Immune Checkpoint Inhibitor Utility

Description/Abstract:	Since the approval of Ipilimumab in 2011 use of immune checkpoint inhibitors (ICIs) has become a mainstay of cancer therapy with the potential to dramatically improve outcomes for even patients with advanced disease. Despite the dramatic potential...
Date:	August 5, 2022

Omnipolar versus Bipolar Electrode Mapping in Patients with Atrial Fibrillation Undergoing Catheter Ablation

Description/Abstract:	Background: Peak-to-peak bipolar voltage varies with electrode orientation, fractionation, and collision events. Novel, omnipolar mapping is less dependent on electrode orientation. While studied in animal models, endocardial omnipolar mapping has...
Date:	August 5, 2022

Optimizing Management of the Central Nervous System in Patients with Acute Lymphoblastic Leukemia Undergoing Allogeneic Stem Cell Transplantation

Description/Abstract:	Optimizing Management of the Central Nervous System in Patients with Acute Lymphoblastic Leukemia Undergoing Allogeneic Stem Cell Transplantation Background: High-risk acute lymphoblastic leukemia (ALL) patients often undergo allogeneic...
Date:	August 5, 2022

Accelerated Epigenetic Aging is Associated with Multiple Cardiometabolic, Hematologic and Renal Abnormalities: a Project Baseline Health Substudy

Description/Abstract:	Background: Epigenetic clocks estimate chronologic age using methylation levels at specific loci. Accelerated biologic aging, defined as higher epigenetic age compared with chronologic age, is associated with adverse health outcomes and mortality....
Date:	August 5, 2022

Social Determinants of Health Data Capture Within National and Health System Data Sources

Description/Abstract:	Background: Equity in organ transplantation cannot be fully achieved without an understanding of how social determinants of health (SDOH) mediate patient outcomes. Unfortunately, SDOH variables are currently inconsistently collected across...
Date:	August 5, 2022

Racial Differences in Over-the-counter Non-steroidal Anti-inflammatory Drug Use Among Individuals at Risk of Adverse Cardiovascular Events

Description/Abstract:	Background Black Americans are disproportionately affected by adverse cardiovascular events (ACEs). Over-the-counter (OTC) non-steroidal anti-inflammatory drugs (NSAIDs) confer increased risk for ACEs, yet racial differences in use of these...
Date:	August 5, 2022

Validation of an Ultrabright Multiplexed Nanorattle Assay for SERS Detection of Synthetic Biomarkers of Head and Neck Cancer

Description/Abstract:	Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide; though it has a high morbidity and mortality, rapid diagnosis and treatment can often be curative. In low-to-middle-income countries, however, this process...
Date:	August 5, 2022

Improved Outcomes in Severe Primary Graft Dysfunction following Heart Transplantation with Donation After Circulatory Death Compared to Donation After Brain Death

Description/Abstract:	Improved Outcomes in Severe Primary Graft Dysfunction following Heart Transplantation with Donation After Circulatory Death Compared to Donation After Brain Death Authors: Austin Ayer; Lauren K. Truby, MD; Jacob N. Schroder, MD; Sarah...
Date:	August 5, 2022

A percentile approach to refining ECG criteria for screening female athletes for cardiac risk

Description/Abstract:	Objectives: Despite known differences in electrocardiographic (ECG) findings by sex, only empirical thresholds for both sexes exist in current ECG guidelines for screening athletes for risk of sudden cardiac death (SCD). We hypothesize that our...
Date:	August 5, 2022

Enterobacter: An Early-Onset Pathogen of Prosthetic Hip and Knee Infections with Poor Prognoses

Description/Abstract:	Background Enterobacter sp. is a gram-negative, often drug-resistant bacillus that is classically identified from mucosal surfaces such as pulmonary or urinary tracts. Despite its virulence, Enterobacter represents a less common pathogen in...
Date:	August 5, 2022

Machine Learning for Improved Size Matching in Lung Transplantation for Restrictive Lung Disease

Description/Abstract:	Background: There is no consensus on optimum graft sizing for lung transplantation in restrictive lung disease (RLD). Matching based on predicted total lung capacity ratios (pTLCdonor:pTLCrecipient, Ratio 1) has been proposed, but pTLC is...
Date:	August 5, 2022

The association between neighborhood quality and cardiovascular risk factors among children with obesity

Description/Abstract:	Background: Socioeconomic and neighborhood factors are associated with large disparities in health including body mass index (BMI) and cardiovascular fitness among pediatric populations. We aim to further characterize these associations in a...
Date:	August 5, 2022

The Impact of Patient-Centered Medical Homes on Healthcare Outcomes

James M. Douglas Oral History Interview, 2022

Don E. Detmer Oral History Interview, 2022

Canine Patient-Derived Organoids as a Model of Tumor Heterogeneity and Drug Sensitivity in Osteosarcoma

Prevalence and Economic Burden of Depression and Anxiety Among Singaporean Adults: Results from a Web Panel

Interneuron transplantation in a mouse organotypic epilepsy model

Obstructive Sleep Apnea as a Risk Factor for Postoperative Cognitive Dysfunction and Postoperative Delirium

Automatic Breast, Fibroglandular Tissue, and Blood Vessel Segmentation in Breast MRI using Convolutional Neural Networks

A Machine Learning Model to Improve Immune Checkpoint Inhibitor Utility

Omnipolar versus Bipolar Electrode Mapping in Patients with Atrial Fibrillation Undergoing Catheter Ablation

Optimizing Management of the Central Nervous System in Patients with Acute Lymphoblastic Leukemia Undergoing Allogeneic Stem Cell Transplantation

Accelerated Epigenetic Aging is Associated with Multiple Cardiometabolic, Hematologic and Renal Abnormalities: a Project Baseline Health Substudy

Social Determinants of Health Data Capture Within National and Health System Data Sources

Racial Differences in Over-the-counter Non-steroidal Anti-inflammatory Drug Use Among Individuals at Risk of Adverse Cardiovascular Events

Validation of an Ultrabright Multiplexed Nanorattle Assay for SERS Detection of Synthetic Biomarkers of Head and Neck Cancer

Improved Outcomes in Severe Primary Graft Dysfunction following Heart Transplantation with Donation After Circulatory Death Compared to Donation After Brain Death

A percentile approach to refining ECG criteria for screening female athletes for cardiac risk

Enterobacter: An Early-Onset Pathogen of Prosthetic Hip and Knee Infections with Poor Prognoses

Machine Learning for Improved Size Matching in Lung Transplantation for Restrictive Lung Disease

The association between neighborhood quality and cardiovascular risk factors among children with obesity

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