Background:
Tracheostomy is a high-risk procedure in children under three years old, with a rate of major post-operative complications as high as 24%. The rate of accidental decannulation (AD), a common complication of tracheostomy associated with...
Background
Despite causing significant morbidity and mortality, non-alcoholic fatty liver disease (NAFLD) is significantly underdiagnosed. Clinical indices developed to easily identify patients with hepatic steatosis and risk for more advanced disease...
Background: It remains unclear whether food insecurity as a marker of poverty is a barrier to accessing health care in low-resource settings, or rather increases care utilization due to more frequent need for care. This study used baseline data from...
Funding: National Institutes of Health/National Cancer Institute StARR Program R38 (5R38-CA245204 to E.J.V.); National Institutes of Health/National Cancer Institute (K08-CA2560450 to Z.J.R.).
Background: Primary central nervous system lymphoma...
Purpose
The diagnosis of neurodegenerative diseases is largely based on clinical suspicion with limited confirmation antemortem. However, neuropathological changes occur years prior to disease presentation. Changes in the retina, an embryologically...
Purpose: Few studies have looked at repeatability of the choroidal vascularity index (CVI) in different OCT imaging modalities. We performed a retrospective image analysis to compare a handheld swept-source research OCT system (UC3) to a gold standard...
Introduction: The Lancet Commission on Global Surgery (2015) outlined several factors needed to sustain a workforce in austere settings. Yet, there is a paucity of literature exploring the personal narratives of these workforce members. There is...
Background
Anthracyclines are effective chemotherapeutics used in >60% of pediatric cancer cases but have a well-documented risk of cardiotoxicity. Existing cardiotoxicity risk calculators do not include cardiovascular risk factors present at the...
Introduction: Prosthetic joint infection (PJI) following joint arthroplasty is a devastating complication. Prior studies have documented an association between PJI and increased prevalence of preoperative depression and elevated risk of new mental...
Antibodies perform both neutralizing and non-neutralizing functions that protect against certain pathogens. A human antibody directed at the SARS-CoV-2 spike protein N-terminal domain (NTD), DH1052, was recently shown to be non-neutralizing yet...
Introduction: While obesity and chronic hypertension are often viewed as confounding the observed relationship between race and maternal morbidity, evidence suggests racism drives development of maternal morbidity risk factors, including obesity and...
Childhood Disintegrative Disorder (CDD) is a poorly understood neurobehavioral disorder of early childhood characterized by acute to subacute profound regression in previously developed language, social behavior, and adaptive functions. The etiology of...
Healthcare inequities in the US impact access to medical treatment for pediatric patients, particularly in conditions like adolescent idiopathic scoliosis (AIS) where nonoperative management is effective. AIS affects 3% of the pediatric population,...
Introduction:
It is currently unclear if postoperative pain experience differs in patients undergoing primary versus repeat cesarean deliveries, with prior studies reporting conflicting results. For instance, some studies have suggested that repeat...
PURPOSE: Three-dimensional (3D) printing enables surgeons to take a more individualized approach to patient management. Commercially available scanning systems can be prohibitively expensive. Fortunately, high-quality 3D imaging is becoming...
INTRODUCTION
Recently, dual-plating of displaced clavicle fractures has become a popular construct to reduce implant prominence while optimizing balanced fixation. Traditionally patients have a limited weight bearing period after clavicle fracture...
Background: While Kambin’s triangle has become an ever more important anatomic window given its proximity to the nerve root, there have been limited studies examining the effect of disease on the corridor. Recent studies have begun implementing 3D...