Traumatic etiology is implicated in up to 12% of the cases of osteoarthritis in the United States. This type of arthritis, termed post traumatic osteoarthritis (PTOA), has been proposed to be mediated in part through an imbalance in inflammatory...
Background: Parents of neonates with seizures report persistent symptoms of depression, anxiety, and post-traumatic stress. We aimed to characterize the parent experience of caring for children impacted by neonatal seizures, including longitudinal...
Background: Neighborhood socioeconomic deprivation is a known contributor to health inequities, though its impact on the care of people with diabetes is not well characterized. Understanding the contribution of systemic forces that drive disparate...
INTRODUCTION
The 5-factor modified Frailty Index (mFI-5) is a concise and effective tool for predicting adverse events after orthopedic operations. However, no studies have assessed its utility in patients undergoing open reduction and internal...
Background: While caregiver coaching can teach caregivers early intervention strategies that they can use with their young autistic child during everyday activities, there is limited access to caregiver coaching in low-resource, culturally and...
Background: Outcomes research in cleft palate care is limited by small sample size, longitudinal care, numerous phenotypic variations, and the lack of a well-established learning health system. The objective of this study is to conduct a critical...
Cochlear and middle ear efferents modulate sensory information in the hearing system, shaping auditory waveforms and refining sound perception. These efferent pathways innervate the middle ear muscles and cochlear outer hair cells; eardrum oscillation...
Background: Sarcoidosis is a multi-system inflammatory disease characterized by noncaseating granulomas, for which the current mainstay of treatment is steroids and/or other immunosuppressing agents. There is a need to better understand the intricacies...
Background: Psoriasis is an autoimmune skin disease associated with inflammatory pulmonary diseases. However, it is unclear whether psoriasis patients are at increased risk for chronic obstructive pulmonary disease (COPD). In addition, the relationship...
Background: Results from computed tomography (CT) in leveled pediatric trauma patients can provide data critical for clinical decision-making. However, in this radio-sensitive population, significant opportunity exists to reduce healthcare waste and...