Caused by the parasite Trypanosoma cruzi, Chagas disease is one of the most neglected tropical diseases in the world and poses a significant burden to the estimated eight million people living with disease. As primary infection is largely asymptomatic,...
Background:
Plasmodium falciparum antigenic diversity compromises the development of lasting immunity. Currently available vaccines for malaria contain a single sequence of P. falciparum circumsporozoite protein (CSP), and protection following...