Index Catalog // MEDSpace

Start Over

Filtering by: Research Type Lab Based

Validation of Hypoxic Red Blood Cell Storage Procedure and Interrogation of its Vasoregulatory Effects

Description/Abstract:	Background: Red blood cells (RBCs), in addition to carrying oxygen, generate and export vasoregulatory mediators as a function of their metabolic context. S- nitrosothiol (SNO) is exported to effect hypoxic vasodilation, a fundamental vascular...
Date:	August 1-2, 2024

Generation of antibodies for the diagnosis of acute and chronic Chagas Disease using phage display technology

Description/Abstract:	Caused by the parasite Trypanosoma cruzi, Chagas disease is one of the most neglected tropical diseases in the world and poses a significant burden to the estimated eight million people living with disease. As primary infection is largely...
Date:	August 1-2, 2024

Evaluating Immunoproteasome Inhibition in Murine Cardiac Transplant Recipients: Can a Novel Therapeutic with Enhanced Specificity Reduce Toxicity and Prevent Antibody-Mediated Damage?

Description/Abstract:	Objective: Cardiac Allograft Vasculopathy (CAV), a process of vascular damage accelerated by antibody-mediated rejection (AMR), is the leading cause of cardiac transplant failure. Proteasome inhibitors (PIs) are utilized to treat AMR; however,...
Date:	August 1-2, 2024

Immuno-informatic Approaches to Identifying Variant-Transcendent Naturally-Acquired Protection against Plasmodium falciparum

Description/Abstract:	Background: Plasmodium falciparum antigenic diversity compromises the development of lasting immunity. Currently available vaccines for malaria contain a single sequence of P. falciparum circumsporozoite protein (CSP), and protection following...
Date:	August 1-2, 2024

Improving Microbial Keratitis Artificial Intelligence Screening Tools Constrained by Limited Data Using Synthetic Generation of Slit Lamp Photos

Description/Abstract:	Background: Artificial Intelligence (AI) models, like those used in diabetic retinopathy screening, require large amounts of data to train. Models for diseases with limited public data like microbial keratitis (MK), a top five cause of blindness...
Date:	August 1-2, 2024

Role of Regulatory T-Cells in the Development of Post-Traumatic Osteoarthritis

Description/Abstract:	Traumatic etiology is implicated in up to 12% of the cases of osteoarthritis in the United States. This type of arthritis, termed post traumatic osteoarthritis (PTOA), has been proposed to be mediated in part through an imbalance in inflammatory...
Date:	August 1-2, 2024

Neighborhood Deprivation and Quality of Comprehensive Diabetes Care: Findings from a National Study of Medicare Advantage

Description/Abstract:	Background: Neighborhood socioeconomic deprivation is a known contributor to health inequities, though its impact on the care of people with diabetes is not well characterized. Understanding the contribution of systemic forces that drive disparate...
Date:	August 1-2, 2024

Neural and Perceptual Correlates of Eye-Movement Related Eardrum Oscillations – a New Window into Brain Function?

Description/Abstract:	Cochlear and middle ear efferents modulate sensory information in the hearing system, shaping auditory waveforms and refining sound perception. These efferent pathways innervate the middle ear muscles and cochlear outer hair cells; eardrum...
Date:	August 1-2, 2024

Molecular Determinants of Sarcoidosis

Description/Abstract:	Background: Sarcoidosis is a multi-system inflammatory disease characterized by noncaseating granulomas, for which the current mainstay of treatment is steroids and/or other immunosuppressing agents. There is a need to better understand the...
Date:	August 1-2, 2024

Fetal Wound Healing: Exploring Regeneration-Linked Factors in Scarless Tissue Repair

Description/Abstract:	Background and Hypothesis Cutaneous wound healing is a complex process that is typically characterized by significant inflammation and fibrosis, culminating in the formation of a scar. Improper wound healing can lead to complications, including...
Date:	August 1-2, 2024