Laser interstitial thermal therapy (LITT) is an emerging modality for hyperthermic ablation of brain tumors. Hyperthermia-induced tumor coagulative necrosis may serve as a source of neoantigen for T-cell priming and a subsequent anti-tumor immune...
Background: While hematopoietic stem cell transplantation (HSCT) is an effective treatment for hematological malignancies, it is associated with several potential complications. Recent studies have associated beta-blocker (BB) use in critical care...
Background: A primary focus of regenerative medicine is to understand the cellular mechanisms
governing tissue regeneration across various species. Mammals generally possess a restricted
regenerative capacity compared to species like zebrafish...
Introduction: Orthopedic procedures often require removing bone or pathological tissue, with traditional methods involving instruments like curettes and rongeurs. However, these methods can be time-consuming and lead to increased blood loss. To...
Background: Gliomas are the most common malignant primary brain tumor. Genomic characterization is necessary for diagnosis and treatment decisions, for which the brain is biopsied and can lead to delays in care, morbidity, and mortality. Here, we...
Background:
Deterioration of children's mental health during the pandemic resulted in the declaration of a national emergency. High rates of psychotropic prescribing among children within the foster care system has been a target of federal and...
BACKGROUND: The purpose of this study was to systematically review complications arising from intramedullary nailing (IMN) of proximal and humeral shaft fractures. This study hypothesized that there would be a low rate of complications and...
Background: In patients with acute pulmonary embolism (PE), early risk stratification is essential in order to determine effective therapeutic management. Right ventricle to left ventricle (RV/LV) ratio measurement is a strong predictor of...
Background: Surgery is the standard of care for early-stage non-small cell lung cancer (NSCLC), with stereotactic body radiotherapy (SBRT) reserved for patients who are not surgical candidates or decline surgery. The role of SBRT for medically...
Background: Thoracic aortic pathology most commonly reviewed at our institution includes aortic aneurysms, acute dissection and acute aortitis, all which are associated with distinct histologic and morphologic features. Spatial transcriptomics...