Background and Hypothesis
Cutaneous wound healing is a complex process that is typically characterized by significant inflammation and fibrosis, culminating in the formation of a scar. Improper wound healing can lead to complications, including...
Background: Single ventricle disease (SVD) is a subtype of congenital heart disease that frequently requires early staged surgical intervention for survival. It is well known that syndromic causes of SVD are associated with worse outcomes....
Background: Cartilage damage is challenging to treat due to its limited self-healing capacity caused by its avascular and aneural nature. However, 3D tissue engineering approaches that utilize biomaterials, additives, and cells offer a promising...
Background: The burden of Acute Myocardial Infarction (AMI) is growing in sub-Saharan Africa. In Tanzania, uptake of diagnostic testing and evidence-based therapy for AMI is suboptimal. We aimed to describe current gaps in evidence-based AMI care...
Background
Historically, the burden of myocardial infarction (MI) in sub-Saharan African nations has been limited, mostly due to the overwhelming impact of communicable diseases on early death. However, with improved access to treatment of...
Background: Despite improvements, patients with advanced cancer often do not receive goal-concordant care at the end of life (EOL). Challenges with prognostication contribute to delays ACP conversations and result in more aggressive care, gaps in...
Background: There are numerous risk factors that affect breast cancer (BC) incidence and mortality, including, but not limited to, age, race, income, insurance status, reproductive patterns, breast density, and germline genetic mutations....
Background
Goals of care (GOC) discussions during advanced serious illness and end-of-life (EOL) care are critical. Institutions are increasingly tracking the frequency and timing of GOC documentation, but large-scale content assessments have...
Background BRAF mutations are common in melanoma, with more than 50% harboring activating BRAF mutations. Though BRAF inhibitors are highly efficacious for nearly half of patients with this BRAF-mutant melanoma, many developing secondary...
Background: Vestibular neuritis and labyrinthitis (VNL) are common causes of vertigo and dizziness. While multiple treatment strategies have been proposed, no established consensus for the optimal way to manage VNL exists. Moreover, no research...