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Filtragem por: Research loc sim Duke University Study Program Clinical Research Study Program (CRSP)

Cerebrospinal Fluid Composition of Infants with Ischemic Stroke

Descrição:	Background: In infants with neurological symptoms, ischemic stroke and bacterial meningitis are possible. To rule out meningitis, clinicians often perform a lumbar puncture. However, there is minimal research describing the cerebrospinal fluid...
Data Criada:	August 1-2, 2024

Distal Clavicle Bone Augmentation for Shoulder Instability

Descrição:	Background: Glenoid bone loss remains one of the most significant risk factors for recurrent instability following surgical management of glenohumeral instability. Controversy exists regarding the optimal procedure for reconstructing glenoid bone...
Data Criada:	August 1-2, 2024

A seat at the table: Family conferences for infants with neurologic conditions

Descrição:	Background: The parent perspective on the value of family conferences in the intensive care unit is not well characterized. We aimed to characterize parents’ perspectives on the value of and opportunities to improve conferences between parents of...
Data Criada:	August 1-2, 2024

Palliative Care Use and End-of-Life Care Quality in ER+/HER2- Metastatic Breast Cancer

Descrição:	Background: Metastatic breast cancer (MBC) is incurable, despite recent therapeutic advances resulting in extended trajectories of disease, especially in estrogen receptor positive (ER+) and human epidermal growth factor-2 negative (HER2-) MBC....
Data Criada:	August 1-2, 2024

Annual Trends and Demographic Variables Associated with Receiving DBS for Patients Admitted to US Hospitals with Dystonia: 2012-2019

Descrição:	Background Differences in the rates of deep brain stimulation (DBS) based on socioeconomic and demographic variables have been investigated for indications such as Parkinson’s disease, essential tremor, and epilepsy. Descriptive studies analyzing...
Data Criada:	August 1-2, 2024

Using generative AI to improve patient comprehension of clinical notes and bridge health literacy gaps in marginalized patient populations

Descrição:	Background: The 21st Century Cures Act provides patients with access to their clinical notes, but most patients, particularly those with limited health literacy (HL), have difficulty understanding and utilizing them for health-based decisions and...
Data Criada:	August 1-2, 2024

Clinical Phenotypes and Outcomes Associated with Improved Left Ventricular Ejection Fraction after Biventricular Pacing

Descrição:	Background: In some patients who receive a cardiac resynchronization therapy (CRT) device, the left ventricular ejection fraction (LVEF) does not improve. Methods: We analyzed patients enrolled in the REVERSE, MADIT-CRT, and BLOCK-HF trials,...
Data Criada:	August 1-2, 2024

Life after neonatal seizures: Characterizing the longitudinal parent experience.

Descrição:	Background: Parents of neonates with seizures report persistent symptoms of depression, anxiety, and post-traumatic stress. We aimed to characterize the parent experience of caring for children impacted by neonatal seizures, including longitudinal...
Data Criada:	August 1-2, 2024

Evaluation of ACCQUIREnet Data Model for a Cleft-Centric Learning Health System

Descrição:	Background: Outcomes research in cleft palate care is limited by small sample size, longitudinal care, numerous phenotypic variations, and the lack of a well-established learning health system. The objective of this study is to conduct a critical...
Data Criada:	August 1-2, 2024

Evaluating Emergency Department and Urgent Care Utilization Trends of Patients with Health-Related Social Needs

Descrição:	Background It is well known that health related social needs (HRSN) impact long-term health outcomes including quality and length of life. Our study sought to examine the relationship between HRSN burden and emergency department (ED) and urgent...
Data Criada:	August 1-2, 2024