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Validation of Hypoxic Red Blood Cell Storage Procedure and Interrogation of its Vasoregulatory Effects

Descrição:	Background: Red blood cells (RBCs), in addition to carrying oxygen, generate and export vasoregulatory mediators as a function of their metabolic context. S- nitrosothiol (SNO) is exported to effect hypoxic vasodilation, a fundamental vascular...
Data Criada:	August 1-2, 2024

Cerebrospinal Fluid Composition of Infants with Ischemic Stroke

Descrição:	Background: In infants with neurological symptoms, ischemic stroke and bacterial meningitis are possible. To rule out meningitis, clinicians often perform a lumbar puncture. However, there is minimal research describing the cerebrospinal fluid...
Data Criada:	August 1-2, 2024

Social connectedness among former US military service members and veterans who died by suicide: a mixed methods exploration

Descrição:	Introduction: A low level of social connectedness is a risk factor and a warning sign for suicide, and it is particularly relevant to understanding suicide in veteran populations. Data from psychological autopsies may provide insights into changes...
Data Criada:	August 1-2, 2024

Building Surgical Character: A Dynamic Simulation Curriculum for Resident Nontechnical Skills

Descrição:	Objective: Previous nontechnical skills simulation curricula in surgery have largely focused on teaching communication skills or empathy in isolation from technical skills, with feedback from one rater perspective. We aimed to develop and pilot an...
Data Criada:	August 1-2, 2024

Assessing medical student wellness in the United States

Descrição:	There is increasing recognition of the importance of medical student wellbeing. The purpose of this study was to determine the characteristics that are associated with lower wellness in medical students. An anonymous, IRB-approved survey was...
Data Criada:	August 1-2, 2024

Exploring the Uneven Distribution of ALS in North Carolina using an Electronic Medical Record Tool

Descrição:	Background: The distribution of amyotrophic lateral sclerosis (ALS) across the world appears to be uneven, which may in part be explained by environmental factors. β-methylamino-L-alanine (BMAA), a neurotoxin produced by cyanobacteria, and...
Data Criada:	August 1-2, 2024

Transvenous extraction of conduction system and lumenless pacing leads

Descrição:	Background: Conduction system pacing (CSP), often accomplished with lumenless pacing leads, is increasingly employed to achieve physiologic ventricular activation. Extraction of CSP leads has raised concerns about damage to the conduction system,...
Data Criada:	August 1-2, 2024

Generation of antibodies for the diagnosis of acute and chronic Chagas Disease using phage display technology

Descrição:	Caused by the parasite Trypanosoma cruzi, Chagas disease is one of the most neglected tropical diseases in the world and poses a significant burden to the estimated eight million people living with disease. As primary infection is largely...
Data Criada:	August 1-2, 2024

Utility of Axillary Staging in Older Patients with HER2-Positive Breast Cancer

Descrição:	Background: The utility of sentinel lymph node biopsy (SLNB) in older patients remains controversial. Advancements in HER2-directed therapy have revolutionized disease response rates and prognosis, supporting efforts to reevaluate the utility of...
Data Criada:	August 1-2, 2024

Exploring malnutrition in head and neck cancer surgery: a novel screening tool for a continuing challenge

Descrição:	Background: Malnutrition is a significant driver of mortality in cancer patients – with estimates that between 10-20% of cancer patients die due to the consequences of malnutrition rather than due to the tumor itself. Patients with head and neck...
Data Criada:	August 1-2, 2024