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Filtern nach: Sammlung 55th Annual Duke School of Medicine Student Research Symposium Study Program Anesthesiology, Surgery, and Environmental Physiology Study Program (ASEP)

Validation of Hypoxic Red Blood Cell Storage Procedure and Interrogation of its Vasoregulatory Effects

Beschreibung:	Background: Red blood cells (RBCs), in addition to carrying oxygen, generate and export vasoregulatory mediators as a function of their metabolic context. S- nitrosothiol (SNO) is exported to effect hypoxic vasodilation, a fundamental vascular...
Datum erstellt:	August 1-2, 2024

Comparison of Inhaled Drug Delivery Across Varying Severities of Subglottic Stenosis

Beschreibung:	Objective: Different staging systems have been developed to assess the severity of laryngotracheal stenosis (LTS). In this study, we assess the effects of stenotic length based on the McCaffrey staging system and constriction in cross-sectional...
Datum erstellt:	August 1-2, 2024

Severe Maternal Morbidity Following Cesarean Hysterectomy for Placenta Accreta Spectrum in the US

Beschreibung:	Objective: Cesarean hysterectomy for placenta accreta spectrum (PAS) is associated with increased risk of post-partum hemorrhage and severe maternal morbidity (SMM). The current literature lacks large multicenter studies of cesarean hysterectomy...
Datum erstellt:	August 1-2, 2024

Evaluating Immunoproteasome Inhibition in Murine Cardiac Transplant Recipients: Can a Novel Therapeutic with Enhanced Specificity Reduce Toxicity and Prevent Antibody-Mediated Damage?

Beschreibung:	Objective: Cardiac Allograft Vasculopathy (CAV), a process of vascular damage accelerated by antibody-mediated rejection (AMR), is the leading cause of cardiac transplant failure. Proteasome inhibitors (PIs) are utilized to treat AMR; however,...
Datum erstellt:	August 1-2, 2024

Material Fatigue of the Artificial Urinary Sphincter Pressure Regulating Balloon: A Mechanical and Microscopic Analysis

Beschreibung:	Background: The artificial urinary sphincter (AUS) is considered the gold standard in the surgical management of stress urinary incontinence, particularly for male patients. The AUS is a fluid-filled hydraulic system comprised of a urethral...
Datum erstellt:	August 1-2, 2024

Utility of Axillary Staging in Older Patients with HER2-Positive Breast Cancer

Beschreibung:	Background: The utility of sentinel lymph node biopsy (SLNB) in older patients remains controversial. Advancements in HER2-directed therapy have revolutionized disease response rates and prognosis, supporting efforts to reevaluate the utility of...
Datum erstellt:	August 1-2, 2024

Exploring malnutrition in head and neck cancer surgery: a novel screening tool for a continuing challenge

Beschreibung:	Background: Malnutrition is a significant driver of mortality in cancer patients – with estimates that between 10-20% of cancer patients die due to the consequences of malnutrition rather than due to the tumor itself. Patients with head and neck...
Datum erstellt:	August 1-2, 2024

Food security and CT-based body composition analysis in patients undergoing bariatric surgery

Beschreibung:	Background. Food insecurity is associated with increased adiposity, obesity-related comorbidities, and lower socioeconomic status. Body composition is commonly measured by bioelectrical impedance; however, artificial intelligence now allows for...
Datum erstellt:	August 1-2, 2024

Effects of Pre-Dive Ketone Food Products on Latency to Central Nervous System Oxygen Toxicity

Beschreibung:	Background Short-term nutritional ketosis may be associated with prolonged latency to central nervous system oxygen toxicity (CNSOT). Ketone food product administration may raise ketone levels more quickly and predictably than dietary...
Datum erstellt:	August 1-2, 2024

Disparities in patient-reported distress in head and neck cancer

Beschreibung:	Background: Distress is common among cancer patients, and impacts morbidity and mortality. Head and neck cancer (HNC) is considered one of the most emotionally distressing of all cancers, and given the stark racial disparities in HNC outcomes, we...
Datum erstellt:	August 1-2, 2024