Laser interstitial thermal therapy (LITT) is an emerging modality for hyperthermic ablation of brain tumors. Hyperthermia-induced tumor coagulative necrosis may serve as a source of neoantigen for T-cell priming and a subsequent anti-tumor immune...
Background: Gliomas are the most common malignant primary brain tumor. Genomic characterization is necessary for diagnosis and treatment decisions, for which the brain is biopsied and can lead to delays in care, morbidity, and mortality. Here, we...