Background BRAF mutations are common in melanoma, with more than 50% harboring activating BRAF mutations. Though BRAF inhibitors are highly efficacious for nearly half of patients with this BRAF-mutant melanoma, many developing secondary...
Background: Plasma and cerebrospinal fluid (CSF) levels of p-tau181 have been associated with Alzheimer’s disease (AD). The retina and vitreous have shown measurable quantities of phosphorylated tau 181 (p-tau181). The aqueous humor, which can be...
BACKGROUND: The purpose of this study was to systematically review complications arising from intramedullary nailing (IMN) of proximal and humeral shaft fractures. This study hypothesized that there would be a low rate of complications and...
Background: Sarcoidosis is a multi-system inflammatory disease characterized by noncaseating granulomas, for which the current mainstay of treatment is steroids and/or other immunosuppressing agents. There is a need to better understand the...
Background: Human migration patterns have been shown to significantly influence the HIV epidemic. Throughout American history, marginalized populations have demonstrated how migration can function as a liberatory tool, as seen in the 20th...
Background: Despite improvements, patients with advanced cancer often do not receive goal-concordant care at the end of life (EOL). Challenges with prognostication contribute to delays ACP conversations and result in more aggressive care, gaps in...
Background: Results from computed tomography (CT) in leveled pediatric trauma patients can provide data critical for clinical decision-making. However, in this radio-sensitive population, significant opportunity exists to reduce healthcare waste...
Background: Ocular surface squamous neoplasia (OSSN) is a potentially vision-threatening malignancy and may be difficult to diagnose as it often appears similar to other lesions such as pterygium and pingueculae. Ocular surface images are easy to...
Background: A primary focus of regenerative medicine is to understand the cellular mechanisms
governing tissue regeneration across various species. Mammals generally possess a restricted
regenerative capacity compared to species like zebrafish...
Background: Race, sex, and age have been shown to influence disparities in work relative value units (wRVUs) generated during adult dermatology encounters.1 Our study investigates whether similar influences exist in pediatric dermatology visits....