Background: Sepsis is a life-threatening response to infection that results in significant morbidity and mortality in children. International standardized guidelines have been developed by organizations such as the Surviving Sepsis Campaign to...
Summary
Background
The dural puncture epidural technique (DPE) is a modification of the combined spinal epidural technique (CSE). Data comparing the two techniques are limited. We performed this randomised study to compare the quality of...
Background: Despite improvements, patients with advanced cancer often do not receive goal-concordant care at the end of life (EOL). Challenges with prognostication contribute to delays ACP conversations and result in more aggressive care, gaps in...
Background: Vestibular neuritis and labyrinthitis (VNL) are common causes of vertigo and dizziness. While multiple treatment strategies have been proposed, no established consensus for the optimal way to manage VNL exists. Moreover, no research...
Background
Long acting injectable (LAI) preexposure prophylaxis (PrEP) has the potential to increase PrEP uptake and adherence. However, the majority of studies investigating opinions about LAI PrEP were theoretical, done prior to its approval....
Background: New childhood cancer diagnoses require timely, multi-specialty care coordination, imposing considerable burdens for families. To better understand these challenges and optimize care delivery, this study aims to 1) track the trajectory...
Background
A previous exploratory analysis of surveillance data at our large academic medical center identified higher CLABSI rates among non-Hispanic Black patients compared to White patients. In the context of a growing understanding of the...
Background: Human migration patterns have been shown to significantly influence the HIV epidemic. Throughout American history, marginalized populations have demonstrated how migration can function as a liberatory tool, as seen in the 20th...
Laser interstitial thermal therapy (LITT) is an emerging modality for hyperthermic ablation of brain tumors. Hyperthermia-induced tumor coagulative necrosis may serve as a source of neoantigen for T-cell priming and a subsequent anti-tumor immune...
Background: Gliomas are the most common malignant primary brain tumor. Genomic characterization is necessary for diagnosis and treatment decisions, for which the brain is biopsied and can lead to delays in care, morbidity, and mortality. Here, we...