Background: Red blood cells (RBCs), in addition to carrying oxygen, generate and export vasoregulatory mediators as a function of their metabolic context. S- nitrosothiol (SNO) is exported to effect hypoxic vasodilation, a fundamental vascular reflex...
Background: In infants with neurological symptoms, ischemic stroke and bacterial meningitis are possible. To rule out meningitis, clinicians often perform a lumbar puncture. However, there is minimal research describing the cerebrospinal fluid (CSF) of...
Objective: Previous nontechnical skills simulation curricula in surgery have largely focused on teaching communication skills or empathy in isolation from technical skills, with feedback from one rater perspective. We aimed to develop and pilot an...
There is increasing recognition of the importance of medical student wellbeing. The purpose of this study was to determine the characteristics that are associated with lower wellness in medical students.
An anonymous, IRB-approved survey was...
Evaluation of pain often relies on subjective patient reported outcomes (PROs) such as the Brief Pain Inventory. Supplementing such measures with objective endpoints can provide a deeper assessment of acute and chronic pain. In the present study, we...
Background: The distribution of amyotrophic lateral sclerosis (ALS) across the world appears to be uneven, which may in part be explained by environmental factors. β-methylamino-L-alanine (BMAA), a neurotoxin produced by cyanobacteria, and...
Background: Conduction system pacing (CSP), often accomplished with lumenless pacing leads, is increasingly employed to achieve physiologic ventricular activation. Extraction of CSP leads has raised concerns about damage to the conduction system, lead...
Caused by the parasite Trypanosoma cruzi, Chagas disease is one of the most neglected tropical diseases in the world and poses a significant burden to the estimated eight million people living with disease. As primary infection is largely asymptomatic,...
Background: The utility of sentinel lymph node biopsy (SLNB) in older patients remains controversial. Advancements in HER2-directed therapy have revolutionized disease response rates and prognosis, supporting efforts to reevaluate the utility of SLNB....
Introduction: Efforts to expand the lung transplant (LTx) donor pool have led to increased use of lungs from donors after circulatory death (DCD), with evidence demonstrating outcomes comparable to those from donors after brain death (DBD). Although...